Which is more effective, minoxidil or finasteride?

In the world of hair care, minoxidil and finasteride are two of the most recommended treatments for hair loss. Both have proven effective in different types of alopecia, especially androgenetic alopecia, but they have different mechanisms of action, formats, and results. Minoxidil is a widely known topical treatment, while finasteride is primarily presented as an oral solution. However, choosing between them or deciding to combine them can be a challenge for those seeking to regain hair density and effectively combat hair loss. The debate over which is more effective—finasteride vs. minoxidil—doesn’t have a single answer, as it depends on various factors such as the cause of the hair loss, the patient’s age, and overall health. Throughout this article, we will explore in depth their characteristics, advantages, risks, and the possibility of combining them to enhance their effects. Is one better than the other? Or is the real secret in using them together? Find out below.

What is minoxidil and how does it work?

Minoxidil is one of the best-known and most widely used treatments for hair loss. Its origins date back to the 1970s, when it was developed as an antihypertensive drug due to its ability to dilate blood vessels. However, one of its most notable side effects was hair growth in treated patients, which led to its study and eventual use as a topical solution for alopecia.

Mechanism of action of minoxidil

Minoxidil acts as a vasodilator, increasing blood flow to the hair follicles. This stimulates follicles in the resting phase (telogen) to enter the active growth phase (anagen). It also strengthens existing hairs and promotes regeneration in areas where follicles are still functional.

Available formats

  • Lotion: The most common form, applied directly to the scalp.
  • Foam: A lighter, easier-to-use version, ideal for people with sensitive skin.
  • Tablets: Used in specific cases under strict medical supervision.

Expected times and results

The effects of minoxidil are not immediate. Patients typically notice a decrease in hair loss after 2-4 months of consistent use. New hair growth is most evident after the sixth month, with maximum results achieved between 8-12 months. It is important to note that the effectiveness of the treatment depends on continued use, as discontinuing treatment may cause hair loss.

Risks and side effects

Minoxidil is generally safe, but it can cause side effects in some cases:
  • Local: Itching, redness, or scaling of the scalp.
  • Systemic: Rarely, it may cause dizziness or increased hair growth on other parts of the body.
  • Initial shedding: During the first few weeks of use, there may be temporary hair loss, a sign that the follicles are entering the growth phase.

What is finasteride and how does it work?

Finasteride for hair loss is an FDA-approved oral treatment for male pattern hair loss. Its history dates back to the 1990s, when it was used as a medication to treat benign prostatic hyperplasia (BPH) due to its ability to shrink the prostate gland. During its clinical use, doctors noticed that many patients experienced a reduction in hair loss, which led to its approval to treat androgenetic alopecia.

Mechanism of action of finasteride

Finasteride works by inhibiting the enzyme 5-alpha reductase, which converts testosterone into dihydrotestosterone (DHT). DHT is a hormone that attacks hair follicles, causing them to become smaller and eventually fall out. By reducing DHT levels, finasteride protects hair follicles and stimulates new hair growth in areas affected by androgenetic alopecia.

Expected times and results

Finasteride treatment for hair loss requires several months of consistent use to show visible results. Most patients notice a decrease in hair loss within 3-6 months, while new hair growth can be noticed between 6-12 months. Results typically stabilize after the first year of treatment.

Finasteride: Side Effects

Although finasteride is effective, it’s important to consider the possible side effects:
  • Decreased libido: Occurs in a small percentage of users.
  • Psychological disturbances: Some patients report symptoms such as anxiety or depression.
  • Gynecomastia: In extremely rare cases, it can cause an increase in breast tissue in men.
In general, side effects usually disappear when treatment is discontinued, but it is always essential to consult a doctor before starting or stopping finasteride use.

Minoxidil vs. Finasteride: Which One Should You Choose?

The debate between minoxidil and finasteride is a common question among those seeking to treat hair loss. Both treatments are effective, but their efficacy varies depending on the type of alopecia, the underlying cause, and the patient’s expectations.

Comparison of effectiveness based on clinical studies

Minoxidil as the most accessible topical treatment
  • Ideal for those seeking treatment without a prescription (in most countries).
  • It is effective on targeted areas of the scalp, especially the crown.
  • Its topical application makes it a preferred option for people who do not wish to take oral medications.
Finasteride as an oral treatment to reduce DHT
  • Considered more effective in cases of male pattern baldness by addressing the root cause: high DHT levels.
  • It has a more comprehensive effect on the scalp, halting the progression of hair loss and promoting thickening of existing hair.

When is one more convenient than the other?

Minoxidil:
  • Patients with early alopecia or localized hair loss.
  • People who prefer to avoid systemic medications.
  • Complementary treatments in combination with techniques such as the FUE technique.
Finasteride:
  • Patients with advanced androgenetic alopecia or a significant family history.
  • Young men with progressive hair loss.
  • Women under medical supervision in selected cases.

Long-term results and sustainability

  • Minoxidil: Works as long as the patient uses it. If the patient stops taking it, the hair they have gained may fall out again within a few months.
  • Finasteride: Offers more stable long-term results, but also requires continued use to maintain its effectiveness.

Is it safe to switch from finasteride to minoxidil or vice versa?

It is possible to switch between these treatments, but it is not recommended to do so abruptly without the guidance of a specialist.
  • Switching from finasteride to minoxidil may lead to temporary hair loss while the follicles adapt to the new treatment.
  • Ideally, discuss with a doctor whether gradual adjustments or a combination of both are necessary to optimize results.

Can minoxidil and finasteride be used at the same time?

Benefits of the combination according to D’Atri Hair Medicine’s clinical experience At D’Atri Hair Medicine, we have observed that the combination of minoxidil and finasteride offers significantly better results than using either treatment separately.
  • Complementarity: While finasteride reduces DHT levels and prevents follicle miniaturization, minoxidil stimulates active hair growth.
  • Accelerated efficacy: The combination helps stop hair loss more quickly and promote more robust hair regeneration.

Synergistic results: How do they enhance their effectiveness together?

Short-term:
  • Faster reduction in hair loss.
  • Visible thickening of thinning hair.
Long-term:
  • Sustained improvement in hair density.
  • Prevention of new areas of hair loss.

Precautions to take when combining both treatments

Although the combination is safe in most cases, it is essential to keep in mind:
  • Medical Supervision: A specialist should evaluate the patient’s medical history to minimize risks.
  • Side Effects: Although rare, effects such as scalp irritation (due to minoxidil) or decreased libido (due to finasteride) may occur.
  • Consistency: Both treatments require continuous use to maintain results.
In conclusion, using minoxidil and finasteride at the same time is a highly effective strategy for treating androgenetic alopecia. However, it is always advisable to consult with a hair health expert to determine the best combination based on each patient’s individual needs.

What is the best treatment for baldness?

When trying to answer the question “What is the best treatment for baldness?”, it’s essential to understand that there’s no single solution that works for every patient. The ideal treatment depends on factors such as the type of alopecia, the stage of progression, and individual goals. At D’Atri Medicina Capilar, we combine our experience with a personalized approach to offer the best options for each patient.

Minoxidil and finasteride in combination with other advanced options

While minoxidil and finasteride are effective alone or in combination, the best results are often achieved when combined with other advanced solutions such as: Platelet-Rich Plasma (PRP): A regenerative treatment that uses the patient’s own growth factors to stimulate hair follicles and enhance the effects of minoxidil and finasteride. FUE Hair Transplant: Ideal for advanced cases of alopecia where bald areas no longer have active follicles. The FUE Technique allows follicular units to be transplanted with precision, achieving a natural and permanent result.

Importance of treatment personalization

At D’Atri Medicina Capilar, each patient is unique. Before starting any treatment, we perform a detailed diagnosis that includes:
  • A thorough medical and hair evaluation.
  • Trichoscopy to analyze the condition of the hair follicles.
  • A review of the patient’s medical history and habits.
This approach allows us to design a comprehensive treatment plan that combines different techniques according to each individual’s specific needs.

D'Atri Hair Medicine patient testimonials

Stories like Martín’s, who regained hair density and confidence after combining an FUE transplant with minoxidil and PRP, are an example of the transformative impact of our treatments. There’s also the case of Ana, who managed to halt the progression of her female pattern baldness with a supervised treatment plan of finasteride and PRP.

Our team of experts: the D'Atri brothers

At D’Atri Medicina Capilar, we have a team of leading specialists in the field of hair medicine:
  • Dr. Gisela D’Atri: An international leader in trichology and hair transplantation. Her experience and leadership guarantee cutting-edge treatments.
  • Dr. Ramiro D’Atri: A specialist in cardiology and aesthetic medicine, he provides a comprehensive approach that combines general health with hair well-being.
  • Dr. Florencia D’Atri: An expert in obstetrics and gynecology and reproductive medicine, she ensures a personalized approach for each patient, including women with alopecia.
Our philosophy combines professionalism, innovation, and a close and empathetic approach, turning each consultation into the beginning of a real transformation.

Conclusion: Minoxidil, Finasteride or Both

Both treatments, minoxidil and finasteride, have proven to be highly effective in combating hair loss. Their effectiveness depends on the type of alopecia and the patient’s individual characteristics.
  • Minoxidil: Ideal for stimulating hair growth and strengthening weakened follicles.
  • Finasteride: Essential for combating the hormonal cause of androgenetic alopecia.
  • In combination: They offer synergistic results and are the preferred option in most cases.

Recommendation based on practical cases

To determine the best treatment, a consultation with a hair health specialist is essential. At D’Atri Medicina Capilar, we combine our experience with the latest technologies to design comprehensive and effective treatments. Don’t wait any longer to take the first step toward your transformation! Schedule your consultation with the hair health experts at D’Atri Medicina Capilar and begin your journey toward healthy hair and greater confidence.

Frequently Asked Questions

Do minoxidil and finasteride have the same side effects?
No, the side effects of minoxidil and finasteride are different because they work differently.
  • Minoxidil: May cause irritation, redness, or scaling of the scalp. Rarely, it may cause dizziness or increased hair growth on other parts of the body.
  • Finasteride: Side effects are more related to hormonal changes, such as decreased libido, emotional disturbances, or, in very rare cases, gynecomastia.
In both cases, side effects are rare, but it is always advisable to consult a doctor if you experience any symptoms.
What happens if I stop using minoxidil or finasteride?
When either treatment is discontinued, the hair follicles that had been stimulated or protected may weaken again. This means that the hair you’ve gained or preserved could gradually fall out over a few months, returning to its pre-treatment state. Therefore, consistency is key to maintaining results. If you’re considering discontinuing treatment, consult a specialist to explore alternatives or adjust your hair care plan.
How does minoxidil affect testosterone?
Minoxidil does not directly affect testosterone levels in the body. Its action focuses on improving blood circulation in the scalp and stimulating hair follicles. Unlike finasteride, which does interact with the conversion of testosterone to DHT, minoxidil is a topical treatment with no hormonal influence.
How much does a treatment at D’Atri Medicina Capilar cost?
The cost of treatments at D’Atri Medicina Capilar varies depending on the type of treatment and the complexity of the case, whether it’s medical treatment, PRP, or FUE hair transplant. To receive a detailed evaluation and a personalized treatment plan, we invite you to schedule a consultation with our experts. Together, we’ll analyze your needs and design the best strategy to achieve your hair goals.
What treatments complement minoxidil and finasteride?
At D’Atri Medicina Capilar, we recommend complementing the use of minoxidil and finasteride with other advanced therapies such as PRP (Platelet-Rich Plasma), microneedling, or even FUE hair transplantation in cases of advanced alopecia. These options enhance the results and guarantee a comprehensive approach.
Why choose D’Atri Medicina Capilar for my treatment?
D’Atri Hair Medicine combines more than 15 years of experience, advanced technology, and a personalized approach to transform our patients’ lives. Our team of experts, led by the D’Atri brothers, is committed to offering effective solutions and a caring approach, ensuring natural and lasting results.